Matrix metalloproteinase 14 overexpression reduces corneal scarring
نویسندگان
چکیده
منابع مشابه
Functional relationship between matrix metalloproteinase-11 and matrix metalloproteinase-14
MMP-11 is a key factor in physiopathological tissue remodeling. As an active form is secreted, its activity must be tightly regulated to avoid detrimental effects. Although TIMP-1 and TIMP-2 reversibly inhibit MMP-11, another more drastic scenario, presumably via hydrolysis, could be hypothesized. In this context, we have investigated the possible implication of MMP-14, since it exhibits a spat...
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ژورنال
عنوان ژورنال: Gene Therapy
سال: 2010
ISSN: 0969-7128,1476-5462
DOI: 10.1038/gt.2010.159